When scientists the world over keep disappearing without a trace, it's up to reporter Polly Perkins (Gwyneth Paltrow) and top aviator Sky Captain (Jude Law) to find out the truth. The dangerous task will involve putting their lives at risk as they travel to treacherous locales, hoping to throw a wrench in the sinful plan of Dr. Totenkopf, who aims to wipe out the planet. Franky Cook (Angelina Jolie) and Dex (Giovanni Ribisi) assist the pair.